A new study published in the Journal of Alzheimer’s Disease showed remarkable improvements in behavior and cognition in patients with severe Alzheimer’s following low-dose radiation treatment.

Morris Freedman, M.D., scientist at Baycrest’s Rotman Research Institute, and head of the neurology division, and senior author of the study said, “The primary goal of a therapy for Alzheimer’s disease should be to improve the patient’s quality of life. We want to optimize their well-being and restore communication with family and friends to avoid social isolation, loneliness, and under-stimulation. Although the study was a small pilot and should be interpreted with caution, our results suggest that low-dose radiation therapy may successfully achieve this.”

In 2015, a case report suggested a patient in hospice with Alzheimer’s disease showed signs of improvement after being treated several times with low-dose radiation to her brain. Her cognition, speech, movement, and appetite were all improved. The patient was eventually discharged from hospice and admitted to a long-term care facility for seniors.

While high doses of radiation are known to create harmful effects on our health, low-dose radiation used in CT scans, for example, can help the body protect and repair itself.

Jerry Cuttler, Ph.D., a retired scientist of Atomic Energy in Canada, has been studying the effects of radiation on health for over 25 years. “Numerous neurological disorders, including Alzheimer’s disease, are thought to be caused in part by oxidative stress that damages all cells, including those in the brain. We have natural protection systems to combat the damage, but they become less effective as we get older. Each dose of radiation stimulates our natural protection systems to work harder – to produce more antioxidants that prevent oxidative damage, to repair more DNA damage, and to destroy more mutated cells,” he said.

In the study, four individuals suffering from severe Alzheimer’s disease were treated with three low doses of radiation spaced two weeks apart. The researchers utilized standardized tests in addition to observation to record patient changes in communication and behavior following treatment. They also collected personal artifacts such as photos, videos, and descriptions from the patients’ family members.

Within one day of the first treatment, three out of four individuals showed improvements such as increased alertness and responsiveness, recognition of loved ones, mobility, social engagement, heightened mood, and more.

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